What is the relationship between consumption of plant n-3 fatty acids and risk of cardiovascular disease? (DGAC 2010)
alpha-linolenic acid (ALA) intake of 0.6-1.2 percent of total calorie will meet current recommendations and may lower cardiovascular disease (CVD) risk, but new evidence is insufficient to warrant greater intake beyond this level. Limited, but supportive evidence suggests that higher intake of n-3 from plant sources may reduce mortality among persons with existing cardiovascular disease.
Conduct randomized controlled trials and prospective observational studies in persons with and without CVD on plant compared to marine n-3 fatty acids. Examine diets rich in plant n-3 fatty acids in subjects with and without adequate intake of n-3 fatty acids from marine sources. Examine the mechanism of action of marine vs. plant n-3 fatty acids for synergies and/or inhibition.
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n-3 Marine and Plants